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A Case of Pulmonary Mucormycosis with Necrotizing Pneumonia and Bronchopleural Fistula Cured by Surgical Resection
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- Summary of article content: Articles about A Case of Pulmonary Mucormycosis with Necrotizing Pneumonia and Bronchopleural Fistula Cured by Surgical Resection 털곰팡이증(mucormycosis)은 Zygomycetes에 속하는 진균에 의하여 발생하는 드문 기회 감염증이다. 위험인자에 따라 다르지만, 비대뇌(rhino-cerebral), 피부, … …
- Most searched keywords: Whether you are looking for A Case of Pulmonary Mucormycosis with Necrotizing Pneumonia and Bronchopleural Fistula Cured by Surgical Resection 털곰팡이증(mucormycosis)은 Zygomycetes에 속하는 진균에 의하여 발생하는 드문 기회 감염증이다. 위험인자에 따라 다르지만, 비대뇌(rhino-cerebral), 피부, …
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털 곰팡이 증
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털 곰팡이 증
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Fatal Rhino-Orbital-Cerebral Mucormycosis Complicated with Thrombosis and Rupture of Mycotic Aneurysm in Distal Internal Carotid Artery
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- Summary of article content: Articles about Fatal Rhino-Orbital-Cerebral Mucormycosis Complicated with Thrombosis and Rupture of Mycotic Aneurysm in Distal Internal Carotid Artery 털곰팡이증(mucormycosis)은 털곰팡이목(order Mucorales)에 속하는 곰팡이에 의한 치명적 인체감염으로, 털곰팡이과(family Mucoraceae)에 속하는 … …
- Most searched keywords: Whether you are looking for Fatal Rhino-Orbital-Cerebral Mucormycosis Complicated with Thrombosis and Rupture of Mycotic Aneurysm in Distal Internal Carotid Artery 털곰팡이증(mucormycosis)은 털곰팡이목(order Mucorales)에 속하는 곰팡이에 의한 치명적 인체감염으로, 털곰팡이과(family Mucoraceae)에 속하는 …
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털곰팡이증: Amphotericin B 치료 실패 후 Posaconazole로 호전된 1예
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- Most searched keywords: Whether you are looking for 털곰팡이증: Amphotericin B 치료 실패 후 Posaconazole로 호전된 1예 털곰팡이증은 그의 진행이 빠르고 예후가 불량한 감염증으로 표준치료로써 AMB가 추천되었다. 저자들은 AMB 치료에 실패하였으나, posaconazole 구제치료에 성공한 비대뇌 … A case of successful posaconazole salvage therapy for rhinocerebral mucormycosis after failure of amphotericin B – Rhinocerebral mucormycosis; Triazoles
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인도 ‘검은 곰팡이증’ 확산 공포…”감염자 1만1천명 넘어” – Sciencetimes
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- Most searched keywords: Whether you are looking for 인도 ‘검은 곰팡이증’ 확산 공포…”감염자 1만1천명 넘어” – Sciencetimes 인도에서 최근 ‘검은 곰팡이증'(정식 명칭은 털곰팡이증)이 유행하면서 감염 환자 수가 1만1천명을 넘어선 것으로 집계됐다. 검은 곰팡이증은 일반적 … 국내외 과학기술동향, 정책, 문화 등 과기계 이슈 정보 제공. 매주 금요일 뉴스레터 발송.
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A Case of Pulmonary Mucormycosis with Necrotizing Pneumonia and Bronchopleural Fistula Cured by Surgical Resection
Pulmonary mucormycosis is an uncommon opportunistic fungal infection associated with diabetes mellitus, leukemia, lymphoma, and other debilitating diseases. It is diagnosed by the pathologic demonstration of typical hyphae, and the condition requires aggressive surgical treatment to reduce the risk of mortality. Pulmonary mucormycosis is associated with various clinical and radiological characteristics. Therefore, a rapid diagnosis and aggressive surgical approach based on early suspicion are important in high-risk patients in order to cure pulmonary mucormycosis. Here, we report the successful treatment of pulmonary mucormycosis in a 58-year-old male with glottic cancer and uncontrolled diabetes who had rapidly progressive necrotizing pneumonia and a bronchopleural fistula via an aggressive pathologic diagnosis and surgical resection. (Korean J Med 2012;83:395-399)
Keywords: Diabetes mellitus; Mucormycosis; Pneumonectomy; Pneumonia; Respiratory tract fistula
Fatal Rhino-Orbital-Cerebral Mucormycosis Complicated with Thrombosis and Rupture of Mycotic Aneurysm in Distal Internal Carotid Artery
Mucormycosis is a rare opportunistic infection caused by fungi of the order Mucorales that typically occurs in patients with diabetes or immunocompromised state. Rhino-orbital-cerebral mucormycosis is the most common type, often has a life-threatening outcome. Mucormycosis has specific vascular tropism complicating mucorthrombosis or mycotic aneurysm. We report a diabetic patient presenting with ophthalmoplegia, orbital necrosis, and contralateral hemiparesis, who suddenly progressed to coma and died of subarachnoid hemorrhage due to the rupture of mycotic aneurysm in distal internal carotid artery.
Key Words: Rhino-orbital-cerebral mucormycosis, Distal internal carotid artery, Mycotic aneurysm
털곰팡이증: Amphotericin B 치료 실패 후 Posaconazole로 호전된 1예
혈당 조절이 불량한 58세 남자 환자가 털곰팡이증으로 진단되었다. 5주 이상의 amphotericin B 치료를 받았으나 병은 진행하여 대뇌로 침범하였다. 이후 그는 경구 posaconazole (800 mg/d 분복)을 6개월 동안 복용 중이다. Posaconazole 구제치료 시작 1주일 후, 환자는 극적인 임상적 호전을 보였고, 부작용 없이 24주째 복용 중이다. 털곰팡이증은 그의 진행이 빠르고 예후가 불량한 감염증으로 표준치료로써 AMB가 추천되었다. 저자들은 AMB 치료에 실패하였으나, posaconazole 구제치료에 성공한 비대뇌 털곰팡이증 1예를 경험하였기에 문헌고찰과 함께 보고한다.
A 58-year-old man with uncontrolled type 2 diabetes mellitus developed rhinocerebral mucormycosis. The infection progressed to intracranial extension despite more than 5 weeks of treatment with amphotericin B. The patient then received oral posaconazole, 800 mg/d, in divided doses for 6 months. Salvage treatment with the new azole antifungal posaconazole resulted in dramatic clinical improvement as early as 1 week after the initiation of therapy. Oral posaconazole continued through 24 weeks of treatment, with marked clinical, mycological, and radiological improvements and no adverse events. Here we review the medical literature on rhinocerebral mucormycosis, which is a rapidly progressive and often fatal infection. The treatment of choice is amphotericin B, which failed in our patient. Our case report suggests that posaconazole appears to be a well tolerated and effective salvage treatment option for rhinocerebral mucormycosis, including disseminated disease.
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